- Short communication
- Open Access
Postural lung recruitment assessed by lung ultrasound in mechanically ventilated children
© The Author(s) 2017
- Received: 27 July 2017
- Accepted: 20 September 2017
- Published: 13 October 2017
Atelectasis is a common finding in mechanically ventilated children with healthy lungs. This lung collapse cannot be overcome using standard levels of positive end-expiratory pressure (PEEP) and thus for only individualized lung recruitment maneuvers lead to satisfactory therapeutic results. In this short communication, we demonstrate by lung ultrasound images (LUS) the effect of a postural recruitment maneuver (P-RM, i.e., a ventilatory strategy aimed at reaerating atelectasis by changing body position under constant ventilation).
Data was collected in the operating room of the Hospital Privado de Comunidad, Mar del Plata, Argentina. Three anesthetized children undergoing mechanical ventilation at constant settings were sequentially subjected to the following two maneuvers: (1) PEEP trial in the supine position PEEP was increased to 10 cmH2O for 3 min and then decreased to back to baseline. (2) P-RM patient position was changed from supine to the left and then to the right lateral position for 90 s each before returning to supine. The total P-RM procedure took approximately 3 min. LUS in the supine position showed similar atelectasis before and after the PEEP trial. Contrarily, atelectasis disappeared in the non-dependent lung when patients were placed in the lateral positions. Both lungs remained atelectasis free even after returning to the supine position.
We provide LUS images that illustrate the concept and effects of postural recruitment in children. This maneuver has the advantage of achieving recruitment effects without the need to elevate airways pressures.
- Lung ultrasound
- Anesthesia-induced atelectasis
- Lung recruitment
- Mechanical ventilation
The incidence of atelectasis in mechanically ventilated children with healthy lungs is as high as 68–100% [1–4]. Anesthesia-induced atelectasis has been well described by different imaging techniques such as CT, MRI and lung ultrasound (LUS) [1–5]. The main mechanism leading to atelectasis formation during anesthesia is a decrease in functional residual capacity due to lung compression through the dysfunctional diaphragm by abdominal content [6, 7]. During such conditions, the trans-pulmonary pressure (Ptp = airways − pleural pressure) is no longer sufficient to offset these compressive forces on the most gravity-dependent parts of the lungs, where Ptp is naturally the lowest. Compression atelectasis has clearly been demonstrated in anesthetized children and adults [3, 7–10].
Rationale of postural lung recruitment
Lung recruitment maneuvers are ventilator strategies that elevate airway pressures for a few breaths to reaerate atelectasis [11, 12]. Such maneuvers are safe and easily to conduct in mechanically ventilated children [3, 13]. However, potential hemodynamic side effects of high intrathoracic pressures necessitate close hemodynamic monitoring and that such maneuvers are performed in normovolemic patients, only .
In this short communication, we explain the rationale of a new type of lung recruitment maneuver—the postural recruitment (P-RM). It can be defined as an active reaeration of atelectatic lung tissue by intentional changes of a patient’s body position under constant ventilatory conditions. This concept makes use of the influence that gravity has on respiratory physiology, more precisely on Ptp. The superimposed pressure within the thorax caused by the lung’s own weight decreases Ptp by approximately 0.25 cmH2O for every 1 cm of ventral-to-dorsal thoracic diameter. Therefore, in supine mechanically ventilated patients Ptp decreases along the gravitational axis causing the lungs to collapse in their most dorsal parts (lowest Ptp) while keeping the ventral zones (highest Ptp) aerated and thus “open” during the entire respiratory cycle . No matter in which body position the patient is placed, dorsal lung zones will always be prone to atelectasis and airways closure [6, 7, 10].
The first principle refers to the relationship between Ptp and body position. It postulates that collapsed tissue in dependent lung zones can be recruited by placing the patient in the opposite position (i.e., from supine to prone or from the left to the right lateral decubitus position). This way, previously collapse lung tissue is now located in the non-dependent position where it is being subjected to the expanding forces of higher Ptps.
The second principle refers to the stabilizing effect of positive end-expiratory pressure (PEEP) on airways and alveoli. It postulates that—provided sufficient PEEP is applied—well ventilated and fully aerated non-dependent lung areas will remain “open” even when becoming dependent again after returning the body to its initial position.
Mechanically ventilated children are a sub-population that could especially benefit from this intervention for two reasons: (1) the respiratory physiology of pediatric patients makes them more susceptible to lung collapse after tracheal intubation than adults [8, 9], and (2) children are usually of light weight and can thus be easily turned by one single operator.
In this short communication, we present lung ultrasound (LUS) images which confirm the recruitment effect of intentional changes of body position in anesthetized children. LUS is a good non-invasive tool for monitoring lung aeration during and after lung recruitment maneuvers in real-time fashion [14–16].
We analyzed three anesthetized children undergoing open inguinal hernia repair. Children aged 12, 24 and 34 months weighing 10, 12 and 18 kg, respectively. After approval by the local Ethical Committee and after obtaining Informed Consent from the parents, patients received general anesthesia under standard monitoring. Their lungs were ventilated in a pressure-controlled mode using an Aespire 7900 (Datex-Ohmeda, GE Healthcare, Helsinki, Finland) with the inspiratory pressure set to achieve a tidal volume of 7 mL/kg (approx. 12 cmH2O) and a respiratory rate adjusted between 20 and 25 bpm to keep end-tidal of carbon dioxide between 35 and 40 mmHg. PEEP was 5 cmH2O, I:E 1:1 and FIO2 0.5.
Testing the reaerating effect of 10 cmH 2 O of PEEP After anesthesia induction in the supine position, PEEP was increased from 5 to 10 cmH2O keeping ventilation constant for 3 min. Then, ventilation returned to baseline settings but keeping PEEP at 8 cmH2O to maintain any potential recruitment that 10 cmH2O of PEEP may have induced.
Testing the effect of postural recruitment Before emergence from anesthesia, patients were placed in the left lateral decubitus position for 90 s at constant ventilation but raising PEEP to 10 cmH2O. Thereafter, patients were turned on their right side for another 90 s. At the end of the 3rd min, patients were placed back in the supine position returning to baseline ventilation, however, at a PEEP of 8 cmH2O to keep the lungs open.
Figure 2 depicts the results of the protocol in one patient (case 1–24 months). LUS images taken at 8 cmH2O of PEEP show that 3 min of ventilation with 10 cmH2O of PEEP in the supine position did not have any measurable recruitment effect. Atelectasis persisted during and after PEEP elevation in all patients. Figure 3 shows the effect of the P-RM in the other two patients (case 2–12 months and case 3–34 months). The Additional file 1: video S1, Additional file 2: video S2 and Additional file 3: video S3 show the corresponding results than Figs. 2 and 3.
By contrast, the changing body positions of the P-RM clearly restored lung aeration in the atelectatic areas at the same ventilator settings. Reaeration of previously collapsed dependent lung areas was always observed as soon as they became non-dependent in the uppermost position; first in the right lung with the patient lying in the left lateral position and then in the left one with the patient in the right lateral decubitus. After the P-RM, both lungs remained free from atelectasis in the final supine position (Figs. 2, 3; Additional file 1: video S1, Additional file 2: video S2 and Additional file 3: video S3). Hemodynamics maintained stable throughout the protocol.
In this short communication, we present LUS images documenting the positive effects of postural recruitment in children. Changes in body position during constant ventilation at 10 cmH2O of PEEP decreased atelectasis without the need to elevate airway pressures as in conventional recruitment maneuvers. Bedside imaging techniques such as LUS can help identify the best settings for a P-RM adapting them to the individual patient.
GT and CMA made the clinical cases. GT, CMA, SHB, ADW, CF, MPM and FSS worked on the interpretation of the findings and in the final edition of the manuscript. All authors read and approved the final manuscript.
The authors declare that they have no competing interests.
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The institutional review board (CIREI) approved this study, its publication and the corresponding written informed consent was obtained from the patient’s relatives.
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