Rothwell PM, Coull AJ, Silver LE, Fairhead JF, Giles MF, Lovelock CE, Redgrave JNE, Bull LM, Welch SJV, Cuthbertson FC, Binney LE, Gutnikov SA, Anslow P, Banning AP, Mant D, Mehta Z: Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study). Lancet 2005,366(9499):1773–1783. doi:10.1016/S0140–6736(05)67702–1 10.1016/S0140-6736(05)67702-1
Article
CAS
PubMed
Google Scholar
Saver JL: Time is brain-quantified. Stroke 2005,37(1):263–266. doi:10.1161/01.STR.0000196957.55928.ab
Article
PubMed
Google Scholar
Hacke W, Kaste M, Bluhmki E, Brozman M, Dávalos A, Guidetti D, Larrue V, Lees KR, Medeghri Z, Machnig T, Schneider D, von Kummer R, Wahlgren N, Toni D: Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008,359(13):1317–1329. doi:10.1056/NEJMoa0804656 10.1056/NEJMoa0804656
Article
CAS
PubMed
Google Scholar
Costalat V, Machi P, Lobotesis K, Maldonado I, Vendrell JF, Riquelme C, Mourand I, Milhaud D, Héroum C, Perrigault P, Arquizan C, Bonafé A: Rescue, combined, and stand-alone thrombectomy in the management of large vessel occlusion stroke using the solitaire device: a prospective 50-patient single-center study: timing, safety, and efficacy. Stroke 2011,42(7):1929–1935. doi:10.1161/STROKEAHA.110.608976 10.1161/STROKEAHA.110.608976
Article
PubMed
Google Scholar
Lichtman JH, Watanabe E, Allen NB, Jones SB, Dostal J, Goldstein LB: Hospital arrival time and intravenous t-PA use in US Academic Medical Centers, 2001–2004. Stroke 2009,40(12):3845–3850. doi:10.1161/STROKEAHA.109.562660 10.1161/STROKEAHA.109.562660
Article
PubMed
Google Scholar
Albers GW, Olivot J: Intravenous alteplase for ischaemic stroke. Lancet 2007,369(9558):249–250. doi:10.1016/S0140–6736(07)60120–2 10.1016/S0140-6736(07)60120-2
Article
PubMed
Google Scholar
Evenson KR, Foraker RE, Morris DL, Rosamond WD: A comprehensive review of prehospital and in-hospital delay times in acute stroke care. Int J Stroke 2009,4(3):187–199. doi:10.1111/j.1747–4949.2009.00276.x 10.1111/j.1747-4949.2009.00276.x
Article
PubMed Central
CAS
PubMed
Google Scholar
Meyer BC: Telestroke evolution: from maximization to optimization. Stroke 2012,43(8):2029–2030. doi:10.1161/STROKEAHA.112.662510 10.1161/STROKEAHA.112.662510
Article
PubMed Central
PubMed
Google Scholar
Puolakka T, Väyrynen T, Häppölä O, Soinne L, Kuisma M, Lindsberg PJ: Sequential analysis of pretreatment delays in stroke thrombolysis. Acad Emerg Med 2010,17(9):965–969. doi:10.1111/j.1553–2712.2010.00828.x 10.1111/j.1553-2712.2010.00828.x
Article
PubMed
Google Scholar
Teuschl Y, Brainin M: Stroke education: discrepancies among factors influencing prehospital delay and stroke knowledge. Int J Stroke 2010,5(3):187–208. 10.1111/j.1747-4949.2010.00428.x
Article
PubMed
Google Scholar
Holscher T, Schlachetzki F, Zimmermann M, Jakob W, Ittner KP, Haslberger J, Bogdahn U, Boy S: Transcranial ultrasound from diagnosis to early stroke treatment. 1. Feasibility of prehospital cerebrovascular assessment. Cerebrovasc Dis 2008,26(6):659–663. doi:10.1159/000166844 10.1159/000166844
Article
PubMed
Google Scholar
Machi P, Costalat V, Lobotesis K, Maldonado IL, Vendrell JF, Riquelme C, Bonafé A: Solitaire FR thrombectomy system: immediate results in 56 consecutive acute ischemic stroke patients. J Neurointerv Surg 2012,4(1):62–66. doi:10.1136/jnis.2010.004051 10.1136/jnis.2010.004051
Article
PubMed Central
PubMed
Google Scholar
Ahmed N, Wahlgren N, Brainin M, Castillo J, Ford GA, Kaste M, Lees KR, Toni D: Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR). Stroke 2009,40(7):2442–2449. doi:10.1161/STROKEAHA.109.548602 10.1161/STROKEAHA.109.548602
Article
PubMed
Google Scholar
Brunser AM, Lavados PM, Hoppe A, Lopez J, Valenzuela M, Rivas R: Accuracy of transcranial Doppler compared with CT angiography in diagnosing arterial obstructions in acute ischemic strokes. Stroke 2009,40(6):2037–2041. 10.1161/STROKEAHA.108.542704
Article
PubMed
Google Scholar
Boddu DB, Sharma VK, Bandaru VCSS, Jyotsna Y, Padmaja D, Suvarna A, Kaul S: Validation of transcranial Doppler with magnetic resonance angiography in acute cerebral ischemia. J Neuroimaging 2011,21(2):e34-e40. 10.1111/j.1552-6569.2009.00412.x
Article
PubMed
Google Scholar
Tsivgoulis G, Sharma VK, Lao AY, Malkoff MD, Alexandrov AV: Validation of transcranial Doppler with computed tomography angiography in acute cerebral ischemia. Stroke 2007,38(4):1245–1249. doi:10.1161/01.STR.0000259712.64772.85 10.1161/01.STR.0000259712.64772.85
Article
PubMed
Google Scholar
Allendoerfer J, Goertler M, von Reutern G: Prognostic relevance of ultra-early doppler sonography in acute ischaemic stroke: a prospective multicentre study. Lancet Neurol 2006,5(10):835–840. doi:10.1016/S1474–4422(06)70551–8 10.1016/S1474-4422(06)70551-8
Article
PubMed
Google Scholar
Malferrari G, Bertolino C, Casoni F, Zini A, Sarra VM, Sanguigni S, Pratesi M, Lochner P, Coppo L, Brusa G, Guidetti D, Cavuto S, Marcello N: The eligible study: ultrasound assessment in acute ischemic stroke within 3 hours. Cerebrovasc Dis 2007,24(5):469–476. 10.1159/000108922
Article
PubMed
Google Scholar
Kaps M, Stolz E, Allendoerfer J: Prognostic value of transcranial sonography in acute stroke patients. Eur Neurol 2008,59(Suppl 1):9–16.
Article
PubMed
Google Scholar
Chernyshev OY, Garami Z, Calleja S, Song J, Campbell MS, Noser EA, Shaltoni H, Chen C, Iguchi Y, Grotta JC, Alexandrov AV: Yield and accuracy of urgent combined carotid/transcranial ultrasound testing in acute cerebral ischemia. Stroke 2005,36(1):32–37. doi:10.1161/01.STR.0000150496.27584.e3 10.1161/01.STR.0000150496.27584.e3
Article
PubMed
Google Scholar
Postert T, Braun B, Meves S, Köster O, Przuntek H, Weber S, Büttner T: Contrast-enhanced transcranial color-coded sonography in acute hemispheric brain infarction. Stroke 1999,30(9):1819–1826. 10.1161/01.STR.30.9.1819
Article
CAS
PubMed
Google Scholar
Zanette EM, Fieschi C, Bozzao L, Roberti C, Toni D, Argentino C, Lenzi GL: Comparison of cerebral angiography and transcranial Doppler sonography in acute stroke. Stroke 1989,20(7):899–903. 10.1161/01.STR.20.7.899
Article
CAS
PubMed
Google Scholar
von Reutern G, Goertler M, Bornstein NM, Del Sette M, Evans DH, Hetzel A, Kaps M, Perren F, Razumovky A, von Reutern M, Shiogai T, Titianova E, Traubner P, Venketasubramanian N, Wong LKS, Yasaka M: Grading carotid stenosis using ultrasonic methods. Stroke 2012,43(3):916–921. doi:10.1161/STROKEAHA.111.636084 10.1161/STROKEAHA.111.636084
Article
PubMed
Google Scholar
Arning C, Widder B, von Reutern GM, Stiegler H, Görtler M: Ultraschallkriterien zur Graduierung von Stenosen der A. carotis interna - Revision der DEGUM-Kriterien und Transfer in NASCET-Stenosierungsgrade (Revision of DEGUM ultrasound criteria for grading internal carotid artery stenoses and transfer to NASCET measurement). Ultraschall Med 2010,31(3):251–257. doi:10.1055/s-0029–1245336 10.1055/s-0029-1245336
Article
CAS
PubMed
Google Scholar
Barber PA, Demchuk AM, Zhang J, Buchan AM: Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS study group. Alberta stroke programme early CT score. Lancet 2000,355(9216):1670–1674. 10.1016/S0140-6736(00)02237-6
Article
CAS
PubMed
Google Scholar
Fiebach J: CT and diffusion-weighted MR imaging in randomized order: diffusion-weighted imaging results in higher accuracy and lower interrater variability in the diagnosis of hyperacute ischemic stroke. Stroke 2002,33(9):2206–2210. doi:10.1161/01.STR.0000026864.20339.CB 10.1161/01.STR.0000026864.20339.CB
Article
CAS
PubMed
Google Scholar
Barlinn K, Alexandrov AV: Vascular imaging in stroke: comparative analysis. Neurotherapeutics 2011. doi:10.1007/s13311–011–0042–4
Google Scholar
Burke JF, Sussman JB, Morgenstern LB, Kerber KA: Time to stroke magnetic resonance imaging. J Stroke Cerebrovasc Dis 2012. doi:10.1016/j.jstrokecerebrovasdis.2012.03.012
Google Scholar
von Kummer R, Bourquain H, Bastianello S, Bozzao L, Manelfe C, Meier D, Hacke W: Early prediction of irreversible brain damage after ischemic stroke at CT. Radiology 2001,219(1):95–100. 10.1148/radiology.219.1.r01ap0695
Article
CAS
PubMed
Google Scholar
Muir KW, Buchan A, von Kummer R, Rother J, Baron J: Imaging of acute stroke. Lancet Neurol 2006,5(9):755–768. doi:10.1016/S1474–4422(06)70545–2 10.1016/S1474-4422(06)70545-2
Article
PubMed
Google Scholar
Chalela JA, Kidwell CS, Nentwich LM, Luby M, Butman JA, Demchuk A, Hill MD, Patronas N, Latour L, Warach S: Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison. Lancet 2007,369(9558):293–298. 10.1016/S0140-6736(07)60151-2
Article
PubMed Central
PubMed
Google Scholar
Wardlaw JM, Mielke O: Early signs of brain infarction at CT: observer reliability and outcome after thrombolytic treatment—systematic review. Radiology 2005,235(2):444–453. doi:10.1148/radiol.2352040262 10.1148/radiol.2352040262
Article
PubMed
Google Scholar
Bhatia R, Hill MD, Shobha N, Menon B, Bal S, Kochar P, Watson T, Goyal M, Demchuk AM: Low rates of acute recanalization with intravenous recombinant tissue plasminogen activator in ischemic stroke: real-world experience and a call for action. Stroke 2010,41(10):2254–2258. doi:10.1161/STROKEAHA.110.592535 10.1161/STROKEAHA.110.592535
Article
CAS
PubMed
Google Scholar
Rahme R, Abruzzo TA, Martin RH, Tomsick TA, Ringer AJ, Furlan AJ, Carrozzella JA, Khatri P: Is intra-arterial thrombolysis beneficial for M2 occlusions? Subgroup (M2) analysis of the PROACT-II trial. Stroke 2013,44(1):240–242. doi:10.1161/STROKEAHA.112.671495 10.1161/STROKEAHA.112.671495
Article
PubMed Central
PubMed
Google Scholar
Kase CS, Furlan AJ, Wechsler LR, Higashida RT, Rowley HA, Hart RG, Molinari GF, Frederick LS, Roberts HC, Gebel JM, Sila CA, Schulz GA, Roberts RS, Gent M: PROACT II Cerebral hemorrhage after intra-arterial thrombolysis for ischemic stroke: the PROACT II trial. Neurology 2001,57(9):1603–1610. 10.1212/WNL.57.9.1603
Article
CAS
PubMed
Google Scholar
Broderick JP, Palesch YY, Demchuk AM, Yeatts SD, Khatri P, Hill MD, Jauch EC, Jovin TG, Yan B, Silver FL, von Kummer R, Molina CA, Demaerschalk BM, Budzik R, Clark WM, Zaidat OO, Malisch TW, Goyal M, Schonewille WJ, Mazighi M, Engelter ST, Anderson C, Spilker J, Carrozzella J, Ryckborst KJ, Janis LS, Martin RH, Foster LD, Tomsick TA: IMS III endovascular therapy after intravenous t-PA versus t-PA alone for stroke. N Engl J Med 2013,368(10):893–903. doi:10.1056/NEJMoa1214300 10.1056/NEJMoa1214300
Article
PubMed Central
CAS
PubMed
Google Scholar
Ciccone A, Valvassori L, Nichelatti M, Sgoifo A, Ponzio M, Sterzi R, Boccardi E, SYNTHESIS Expansion Investigators: Endovascular treatment for acute ischemic stroke. N Engl J Med 2013,368(10):904–913. doi:10.1056/NEJMoa1213701 10.1056/NEJMoa1213701
Article
PubMed Central
CAS
PubMed
Google Scholar
Mikulik R, Alexandrov AV, Ribo M, Garami Z, Porche NA, Fulep E, Grotta JC, Wojner-Alexandrov AW, Choi JY: Telemedicine-guided carotid and transcranial ultrasound: a pilot feasibility study. Stroke 2006,37(1):229–230. doi:10.1161/01.STR.0000196988.45318.97 10.1161/01.STR.0000196988.45318.97
Article
CAS
PubMed
Google Scholar
Ziegler V, Rashid A, Müller-Gorchs M, Kippnich U, Hiermann E, Kögerl C, Holtmann C, Siebler M, Griewing B: Einsatz mobiler computing-systeme in der präklinischen schlaganfallversorgung. Ergebnisse aus der stroke-angel-initiative im rahmen des BMBF-projekts PerCoMed (Mobile computing systems in preclinical care of stroke. Results of the stroke angel initiative within the BMBF project PerCoMed). Anaesthesist 2008,57(7):677–685. doi:10.1007/s00101–008–1395-x 10.1007/s00101-008-1395-x
Article
CAS
PubMed
Google Scholar
Ebinger M, Rozanski M, Waldschmidt C, Weber J, Wendt M, Winter B, Kellner P, Baumann A, Malzahn U, Heuschmann PU, Fiebach JB, Endres M, Audebert HJ: PHANTOM-S: the prehospital acute neurological therapy and optimization of medical care in stroke patients - study. Int J Stroke 2012,7(4):348–353. doi:10.1111/j.1747–4949.2011.00756.x
PubMed
Google Scholar
Walter S, Kostopoulos P, Haass A, Keller I, Lesmeister M, Schlechtriemen T, Roth C, Papanagiotou P, Grunwald I, Schumacher H, Helwig S, Viera J, Körner H, Alexandrou M, Yilmaz U, Ziegler K, Schmidt K, Dabew R, Kubulus D, Liu Y, Volk T, Kronfeld K, Ruckes C, Bertsch T, Reith W, Fassbender K: Diagnosis and treatment of patients with stroke in a mobile stroke unit versus in hospital: a randomised controlled trial. Lancet Neurol 2012,11(5):397–404. doi:10.1016/S1474–4422(12)70057–1 10.1016/S1474-4422(12)70057-1
Article
PubMed
Google Scholar
Skorning M, Bergrath S, Rörtgen D, Brokmann J, Beckers S, Protogerakis M, Brodziak T, Rossaint R: “E-Health“ in der Notfallmedizin - das Forschungsprojekt Med-on-@ix. Anaesthesist 2009,58(3):285–292. doi:10.1007/s00101–008–1502-z 10.1007/s00101-008-1502-z
Article
CAS
PubMed
Google Scholar
Weber JE, Ebinger M, Rozanski M, Waldschmidt C, Wendt M, Winter B, Kellner P, Baumann A, Fiebach JB, Villringer K, Kaczmarek S, Endres M, Audebert HJ: Prehospital thrombolysis in acute stroke: results of the PHANTOM-S pilot study. Neurology 2013,80(2):163–168. 10.1212/WNL.0b013e31827b90e5
Article
CAS
PubMed
Google Scholar
Silva GS, Farrell S, Shandra E, Viswanathan A, Schwamm LH: The status of telestroke in the United States: a survey of currently active stroke telemedicine programs. Stroke 2012,43(8):2078–2085. doi:10.1161/STROKEAHA.111.645861 10.1161/STROKEAHA.111.645861
Article
PubMed
Google Scholar
Liman TG, Winter B, Waldschmidt C, Zerbe N, Hufnagl P, Audebert HJ, Endres M: Telestroke ambulances in prehospital stroke management: concept and pilot feasibility study. Stroke 2012,43(8):2086–2090. doi:10.1161/STROKEAHA.112.657270 10.1161/STROKEAHA.112.657270
Article
PubMed
Google Scholar
Reiner-Deitemyer V, Teuschl Y, Matz K, Reiter M, Eckhardt R, Seyfang L, Tatschl C, Brainin M: Helicopter transport of stroke patients and its influence on thrombolysis rates: data from the Austrian Stroke Unit Registry. Stroke 2011,42(5):1295–1300. 10.1161/STROKEAHA.110.604710
Article
PubMed
Google Scholar
Audebert HJ, Schenkel J, Heuschmann PU, Bogdahn U, Haberl RL: Effects of the implementation of a telemedical stroke network: the Telemedic Pilot Project for Integrative Stroke Care (TEMPiS) in Bavaria, Germany. Lancet Neurol 2006,5(9):742–748. doi:10.1016/S1474–4422(06)70527–0 10.1016/S1474-4422(06)70527-0
Article
PubMed
Google Scholar
van Zon K, Lord WP, Lagor C, Theiss S, Brosig T, Siebler M: Stroke navigator—a clinical decision support system for acute stroke. AMIA Annu Symp Proc 2008, 6: 1227.
Google Scholar