Case 1
A 79-year-old female presented to the Emergency Department (ED) with right upper quadrant (RUQ) abdominal pain radiating to the right flank for 2 weeks. Symptoms were associated with subjective fevers and anorexia. The patient denied nausea or vomiting. Her past medical history was significant for hypertension, hyperlipidemia and hypothyroidism. Vital signs were normal. Laboratory tests including white blood cell count, total bilirubin and liver function tests were all normal. A RUQ ultrasound was remarkable for echogenic shadowing seen from the level of the gallbladder fossa representing a gallbladder filled with stones (Fig. 1). No sonographic Murphy’s sign was elicited. There was no gallbladder wall thickening. The patient had resolution of her abdominal pain and was discharged with outpatient surgical follow-up. 19 days later, an elective laparoscopic cholecystectomy was performed. The pathology report was consistent with a diagnosis of acute and chronic cholecystitis.
Case 2
A 29-year-old male presented to the Emergency Department with RUQ pain associated with nausea and vomiting. The patient had no significant past medical history. The vital signs were normal. The physical exam was significant only for RUQ tenderness. The patient was discharged from the Emergency Department diagnosed with cholelithiasis after evaluation with normal laboratory results, normal computed tomography (CT) scan of the abdomen and an ultrasound that demonstrated the WES triad. The patient returned to the Emergency Department 1 month later with similar symptoms and was discharged after a similar work-up. The repeat ultrasound revealed the WES triad and was again interpreted as cholelithiasis. The patient returned to the Emergency Department 3 days later with worsening right upper quadrant pain and nausea. Laboratory results were noncontributory. In light of the multiple visits, the patient was admitted to the surgical team. The patient had an uneventful surgery, and pathology results reported a diagnosis of acute and chronic cholecystitis.
Case 3
A 77-year-old male visited our Emergency Department with 3 days of nausea and vomiting with abdominal fullness. The patient’s medical history was significant for hypertension, hypercholesterolemia and hypothyroidism. Initial vital signs were significant for tachycardia of 112 beats/min. The physical examination was noncontributory. Laboratory results were significant for elevated white blood cell count of 20.1 K/μL (normal range, 4.8–10.8 K/μL). Ultrasound showed the WES triad. At admission, CT scan of the abdomen revealed a small bowel obstruction due to a 2.2 cm calcification in the terminal ileum, consistent with a gallstone ileus. The overall CT pattern was suspicious for a gallbladder that formed a fistula into the adjacent bowel, likely the proximal duodenum, thus leading to a gallstone ileus. The patient was admitted to the surgical service. During his operation, it was confirmed that the patient had a cholecystoduodenal fistula. The surgical pathology of the gallbladder reported chronic cholecystitis.