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Table 1 Baseline characteristics of patients with aortic valve regurgitation (AR)

From: Doppler flow morphology characteristics of epiaortic arteries in aortic valve pathologies: a retrospective study on a cohort of patients with ischemic stroke

Clinical parameters

Aortic valve regurgitation (AR) (n = 482)

P value

No AR (n = 838)

Minimal AR (n = 100)

Mild AR (n = 282)

Moderate AR (n = 96)

Severe AR (n = 4)

Age (mean ± SD)

67.2 ± 14.8

71.2 ± 12.1

77 ± 10.9

79.5 ± 10.9

71.8 ± 16.9

 < 0.001

Gender (n, % male)

452 (53.9)

64 (64)

139 (49.3)

41 (42.7)

4 (100)

0.061

Ischemic stroke (n, %)

478 (57)

57 (57)

183 (64.9)

70 (72.9)

3 (75)

0.01

Coronary heart disease (n, %)

111 (13.2)

14 (14)

53 (18.8)

21 (21.9)

0 (0)

0.05

Heart failure (n, %)

62 (7.4)

6 (6)

26 (9.2)

14 (14.6)

2 (50)

0.003

Hypertension (n, %)

550 (65.6)

71 (71)

208 (73.8)

69 (71.9)

4 (100)

0.052

Diabetes mellitus type 2 (n, %)

167 (19.9)

22 (22)

64 (22.7)

23 (24)

0 (0)

0.609

Hyperlipidemia (n, %)

236 (28.2)

30 (30)

73 (25.9)

22 (22.9)

0 (0)

0.495

Nicotine consume (n, %)

195 (23.3)

12 (12)

25 (8.9)

11 (11.5)

1 (25)

0.1

Obesity (n, %)

95 (11.3)

8 (8)

27 (9.6)

3 (3.1)

0 (0)

0.108

Peripheral artery disease (PAD) (n, %)

25 (3)

2 (2)

5 (1.8)

2 (2.1)

0 (0)

0.807

Renal failure (n, %)

57 (6.8)

5 (5)

31 (11)

15 (15.6)

0 (0)

0.008

Atrial fibrillation (n, %)

136 (16.2)

25 (25)

87 (30.9)

34 (35.4)

1 (25)

0.01

  1. SD standard deviation, differences were analyzsed using Chi-square test and ANOVA
  2. % of patients within each group, n number of patients, AR aortic valve regurgitation