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Table 4 Factors associated with concordance or discordance between SARS-CoV-2 RT-PCR and POCUS diagnosis of SARS-CoV-2

From: Diagnostic accuracy of lung ultrasound for SARS-CoV-2: a retrospective cohort study

SARS-CoV-2 RT-PCR

Negative

Positive

Negative

Positive

p value

POCUS SARS-CoV-2

Negative

Negative

Positive

Positive

N

58

13

23

80

 

Body mass index, kg/m2, mean (SD)a

29.3 (8.1)

36.5 (9.4)

25.4 (6.3)

29.1 (5.6)

< 0.001

Number of lung fields visualized, median (IQR)

12 (8, 12)

11 (10, 12)

11 (9, 12)

12 (10, 12)

0.38

Lung Ultrasound Score, mean (SD)

1.1 (1.6)

0.6 (0.9)

6.3 (3.2)

10.8 (4.5)

< 0.001

Days between symptom onset and test

     

 POCUS, median (IQR)

3 (2, 5)

6 (4, 8)

3 (2, 6)

9.0 (6.0, 14.0)

< 0.001

 RT-PCR, median (IQR)

0 (0, 0)

3.0 (0, 5)

0 (0, 1)

2 (0, 6)

< 0.001

Number of comorbidities, no (%)

     

 0

32 (55%)

7 (54%)

5 (22%)

57 (71%)

0.041

 1

19 (33%)

4 (31%)

11 (48%)

19 (24%)

 2

7 (12%)

1 (8%)

3 (13%)

4 (5%)

 3

0 (0%)

1 (8%)

4 (17%)

0 (0%)

Comorbidities, no (%)

     

Interstitial lung disease

0 (0%)

1 (8%)

6 (26%)

0 (0%)

< 0.001

 Asthma

6 (10%)

1 (8%)

2 (9%)

11 (14%)

0.84

 COPD (without severe emphysematous changes)

6 (10%)

1 (8%)

3 (13%)

2 (2%)

0.18

 Heart failure

14 (24%)

4 (31%)

13 (57%)

8 (10%)

< 0.001

  EF ≤ 35%

2 (3%)

1 (8%)

27 (30%)

1 (1%)

< 0.001

 HIV/AIDS CD4 < 200

2 (3%)

0 (0%)

2 (9%)

1 (1%)

0.26

 Immunosuppression

4 (7%)

2 (15%)

1 (4%)

3 (4%)

0.39

 ESRD

1 (2%)

0 (0%)

2 (9%)

2 (2%)

0.32

  1. EF ejection fraction, HIV/AIDS human immunodeficiency virus/acquired immunodeficiency syndrome, ESRD end-stage renal disease, IQR interquartile range
  2. a7% missing