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Table 4 Factors associated with concordance or discordance between SARS-CoV-2 RT-PCR and POCUS diagnosis of SARS-CoV-2

From: Diagnostic accuracy of lung ultrasound for SARS-CoV-2: a retrospective cohort study

SARS-CoV-2 RT-PCR Negative Positive Negative Positive p value
POCUS SARS-CoV-2 Negative Negative Positive Positive
N 58 13 23 80  
Body mass index, kg/m2, mean (SD)a 29.3 (8.1) 36.5 (9.4) 25.4 (6.3) 29.1 (5.6) < 0.001
Number of lung fields visualized, median (IQR) 12 (8, 12) 11 (10, 12) 11 (9, 12) 12 (10, 12) 0.38
Lung Ultrasound Score, mean (SD) 1.1 (1.6) 0.6 (0.9) 6.3 (3.2) 10.8 (4.5) < 0.001
Days between symptom onset and test      
 POCUS, median (IQR) 3 (2, 5) 6 (4, 8) 3 (2, 6) 9.0 (6.0, 14.0) < 0.001
 RT-PCR, median (IQR) 0 (0, 0) 3.0 (0, 5) 0 (0, 1) 2 (0, 6) < 0.001
Number of comorbidities, no (%)      
 0 32 (55%) 7 (54%) 5 (22%) 57 (71%) 0.041
 1 19 (33%) 4 (31%) 11 (48%) 19 (24%)
 2 7 (12%) 1 (8%) 3 (13%) 4 (5%)
 3 0 (0%) 1 (8%) 4 (17%) 0 (0%)
Comorbidities, no (%)      
Interstitial lung disease 0 (0%) 1 (8%) 6 (26%) 0 (0%) < 0.001
 Asthma 6 (10%) 1 (8%) 2 (9%) 11 (14%) 0.84
 COPD (without severe emphysematous changes) 6 (10%) 1 (8%) 3 (13%) 2 (2%) 0.18
 Heart failure 14 (24%) 4 (31%) 13 (57%) 8 (10%) < 0.001
  EF ≤ 35% 2 (3%) 1 (8%) 27 (30%) 1 (1%) < 0.001
 HIV/AIDS CD4 < 200 2 (3%) 0 (0%) 2 (9%) 1 (1%) 0.26
 Immunosuppression 4 (7%) 2 (15%) 1 (4%) 3 (4%) 0.39
 ESRD 1 (2%) 0 (0%) 2 (9%) 2 (2%) 0.32
  1. EF ejection fraction, HIV/AIDS human immunodeficiency virus/acquired immunodeficiency syndrome, ESRD end-stage renal disease, IQR interquartile range
  2. a7% missing