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Table 1 Baseline characteristics by SARS-CoV-2 RT-PCR results, N = 174

From: Diagnostic accuracy of lung ultrasound for SARS-CoV-2: a retrospective cohort study

 

Overall

RT-PCR result

p value

 

Negative

Positive

N

174

81

93

 

Age, mean (SD)

53.1 (16.8)

51.9 (19.2)

54.2 (14.3)

0.37

Male, no. (%)

92 (53%)

40 (49%)

52 (56%)

0.39

Race, no. (%)

   

< 0.001

 Caucasian

66 (38%)

36 (44%)

30 (32%)

 African American

33 (19%)

4 (5%)

29 (31%)

 Hispanic or Asian

75 (43%)

41 (51%)

34 (37%)

Body mass index, kg/m2, mean (SD)a

29.1 (7.2)

28.1 (7.8)

30.0 (6.6)

0.098

Number of comorbidities, no. (%)

0.013

 0

101 (58.0%)

37 (46%)

64 (69%)

 1

53 (30.5%)

30 (37%)

23 (25%)

 2

15 (8.6%)

10 (12%)

5 (5%)

 3

5 (2.9%)

4 (5%)

1 (1%)

Interventions needed, no. (%)

 High-flow nasal cannula oxygen

10 (5.7%)

1 (1%)

9 (10%)

0.017

Intubation

25 (14.4%)

5 (6%)

20 (22%)

0.004

Comorbidities, no. (%)

 Interstitial lung disease

7 (4%)

6 (7%)

1 (1%)

0.034

 Asthma

20 (12%)

8 (10%)

12 (13%)

0.53

 COPD

12 (7%)

9 (11%)

3 (3%)

0.041

 Heart failure

39 (22%)

27 (33%)

12 (13%)

0.001

  EF ≤ 35%

11 (6%)

9 (11%)

2 (2%)

0.015

 HIV/AIDS CD4 < 200

5 (3%)

4 (5%)

1 (1%)

0.13

 Immunosuppression

10 (6%)

5 (6%)

5 (5%)

0.82

ESRD

5 (3%)

3 (4%)

2 (2%)

0.54

Lung Ultrasound Score, mean (SD)

6.2(5.7)

2.6 (3.2)

9.4 (5.5)

< 0.001

Positive findings by lung field, no. (%)

 L1

47 (27%)

8 (10%)

39 (42%)

< 0.001

 L2

40 (23%)

9 (11%)

31 (33%)

< 0.001

 L3

67 (39%)

16 (20%)

51 (55%)

< 0.001

 L4

39 (22%)

10 (12%)

29 (31%)

0.003

 L5

59 (34%)

9 (11%)

50 (54%)

< 0.001

 L6

55 (32%)

13 (16%)

42 (45%)

< 0.001

 R1

50 (29%)

7 (9%)

43 (46%)

< 0.001

 R2

56 (32%)

10 (12%)

46 (49%)

< 0.001

 R3

62 (36%)

9 (11%)

53 (57%)

< 0.001

 R4

31 (18%)

10 (12%)

21 (23%)

0.078

 R5

65 (37%)

8 (10%)

57 (61%)

< 0.001

 R6

52 (30%)

6 (7%)

46 (49%)

< 0.001

Days between symptom onset and test

 RT-PCR, median (IQR)

3 (2, 7)

3 (2, 5)

5, (3, 7)

< 0.001

 POCUS, median (IQR)

6 (3, 10)

3 (2, 6)

8 (6, 14)

< 0.001

Extent of lung findings, no. (%)

 No findings

53 (31%)

42 (52%)

11 (12%)

< 0.001

 Single field involvement

16 (9%)

102 (15%)

4 (4%)

 Multiple unilateral field involvement

11 (6%)

6 (7%)

5 (5%)

 Bilateral field involvement

94 (54%)

21 (26%)

73 (78%)

  1. EF ejection fraction, HIV/AIDS human immunodeficiency virus/acquired immunodeficiency syndrome, ESRD end-stage renal disease, IQR interquartile range
  2. a6.9% missing