Table 4 Simple regression models of Cox adjusted to the incidence rate of stroke recurrence due to each independent variable

Sociodemographic profile

 Sex, Male

0.57

1.16

0.25

0.620

1.77

0.18

17.0

 Age (years)

0.00

0.04

0.00

0.988

1.00

0.93

1.1

 Race, Non-white

− 3.33

5.48

0.37

0.543

0.04

0.00

1642.1

Risk factors

 Hypertension

3.28

5.85

0.31

0.576

26.47

0.00

3.E + 06

 Smoking

0.95

1.16

0.67

0.412

2.58

0.27

24.8

 Obesity

− 3.09

9.75

0.10

0.752

0.05

0.00

9.E + 06

 Diabetes

0.99

1.00

0.98

0.323

2.69

0.38

19.1

 Dyslipidemia

1.72

1.00

2.94

0.086

5.55

0.78

39.4

 Chagas disease

− 3.12

8.49

0.14

0.714

0.04

0.00

8.E + 05

 Prior stroke

1.87

1.16

2.62

0.106

6.48

0.67

62.3

 Prior CHF

1.48

1.16

1.64

0.200

4.39

0.46

42.2

 Prior AMI

1.12

1.16

0.94

0.331

3.07

0.32

29.5

 Prior CAD

2.20

1.00

4.82

0.028

9.00

1.27

63.9

Clinical profile

 NIHSS

− 0.11

0.10

1.10

0.294

0.90

0.74

1.1

 Previous mRS

0.18

0.52

0.12

0.729

1.20

0.44

3.3

 Wake-up stroke

0.53

1.16

0.21

0.646

1.70

0.18

16.3

 Time to monitoring < 24 h

1.52

1.16

1.73

0.188

4.57

0.48

43.9

Etiologic investigation

 Atrial fibrillation

− 0.06

1.16

0.00

0.957

0.94

0.10

9.0

 Atrial flutter

− 3.06

11.87

0.07

0.797

0.05

0.00

6.E+08

 CHF

− 3.03

16.69

0.03

0.856

0.05

0.00

8.E+12

 PFO

− 3.03

16.69

0.03

0.856

0.05

0.00

8.E+12

 Extracardiac shunt

− 3.01

23.54

0.02

0.898

0.05

0.00

5.E+18

 Debris in aortic arch

− 3.03

16.69

0.03

0.856

0.05

0.00

8.E+12

 Carotid atheromatous

0.74

1.16

0.42

0.519

2.11

0.22

20.2

 Carotid dissection

− 3.03

16.69

0.03

0.856

0.05

0.00

8.E+12

 Symptomatic carotid

0.60

1.16

0.27

0.605

1.82

0.19

17.5

 Intracranial stenosis

− 3.09

9.75

0.10

0.752

0.05

0.00

9.E+06

Treatment

 Thrombolysis

0.08

1.16

0.01

0.942

1.09

0.11

10.5

MES

 Presence of MES

2.58

1.00

6.65

0.010

13.18

1.86

93.64