Table 3 Simple and multiple regression logistics between confounder factors with outcomes
Variables | Simple regression (univariate analysis) | Multiple regression (multivariate analysis) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
mRS 0–2 | Death | Recurrence | mRS 0–2 | Death | Recurrence | |||||||
n (%) | P | n (%) | P | n (%) | P | P | OR (CI95%) | P | OR (IC95%) | P | OR (CI95%) | |
Sex | 0.548 | 0.851 | 1.000 | |||||||||
Male | 44 (62.9) | 11 (15.7) | 3 (2.4) | |||||||||
Female | 23 (56.1) | 7 (17.1) | 1 (4.3) | |||||||||
Age (years) | – | 0.002 | – | 0.005 | – | 0.986 | 0.036 | 0.96 (0.92–1.0) | 0.014 | 1.07 (1.01–1.12) | ||
Race | 0.366 | 0.187 | 1.000 | |||||||||
Caucasian | 52 (57.8) | 17 (18.9) | 4 (4.4) | |||||||||
Non-Caucasian | 15 (75.7) | 1 (5.0) | 0 | |||||||||
Hypertension | 0.132 | 0.46 | 1.000 | |||||||||
Yes (n = 93) | 59 (63.4) | 13 (14.0) | 4 (4.3) | |||||||||
No (n = 18) | 8 (44.4) | 5 (27.8) | 0 | |||||||||
NIHSS at admission | – | < 0.001 | – | <0.001 | – | 0.295 | 0.000 | 0.80 (0.73–0.87) | 0.000 | 1.16 (1.07–1.26) | ||
Prior mRS | – | 0.014 | – | 0.876 | NC | – | 0.002 | 0.31 (0.14–0.66) | ||||
Hemorrhagic transformation | 0.111 | 0.317 | 1.000 | |||||||||
Yes | 2 (28.6) | 2 (28.6) | 0 | |||||||||
No | 65 (62.5) | 16 (15.4) | 4 (3.8) | |||||||||
Smoking | 0.002 | 0.158 | 0.623 | 0.054 | 2.83 (0.98–8.15) | |||||||
Yes (n = 60) | 44 (73.3) | 7 (11.7) | 3 (5.0) | |||||||||
No | 23 (45.1) | 11 (21.6) | 1 (2.0) | |||||||||
Obesity | 0.680 | 1.000 | 1.000 | |||||||||
Yes (n = 6) | 3 (50.0) | 1 (16.7) | 0 | |||||||||
No (n = 105) | 64 (61.0) | 17 (16.2) | 4 (3.8) | |||||||||
Diabetes | 0.206 | 0.280 | 0.295 | |||||||||
Yes (n = 30) | 21 (70.0) | 3 (18.5) | 2 (6.7) | |||||||||
No (n = 81) | 46 (56.8) | 15 (10.0) | 2 (2.5) | |||||||||
Dyslipidemia | 0.182 | 0.298 | 0.110 | |||||||||
Yes (n = 17) | 13 (76.5) | 1 (5.9) | 2 (11.8) | |||||||||
No (n = 94) | 54 (57.4) | 17 (18.1) | 2 (2.1) | |||||||||
Chagas disease | 0.710 | 0.350 | 1.000 | |||||||||
Yes (n = 8) | 4 (50.0) | 0 | 0 | |||||||||
No (n = 103) | 63 (61.2) | 18 (17.5) | 4 (3.9) | |||||||||
Prior stroke | 0.122 | 0.523 | 0.099 | |||||||||
Yes (n = 36) | 18 (50.0) | 7 (19.4) | 3 (8.3) | |||||||||
No (n = 75) | 49 (65.3) | 11 (14.7) | 1 (1.3) | |||||||||
Prior AMI | 0.287 | 1.000 | 0.345 | |||||||||
Yes (n = 11) | 5 (45.5) | 2 (18.2) | 1 (9.1) | |||||||||
No (n = 100) | 62 (62.0) | 16 (16.0) | 3 (3.0) | |||||||||
CAD | 0.879 | 0.687 | 0.057 | |||||||||
Yes (n = 12) | 7 (58.3) | 1 (8.3) | 2 (16.7) | |||||||||
No (n = 99) | 60 (60.6) | 17 (17.2) | 2 (2.0) | |||||||||
Depression | 1.000 | 0.587 | 0.202 | |||||||||
Yes (n = 6) | 4 (60.6) | 0 | 1 (16.7) | |||||||||
No (n = 105) | 63 (50.0) | 18 (17.1) | 3 (2.9) | |||||||||
Wake-up stroke | 0.943 | 1.000 | 0.512 | |||||||||
Yes (n = 18) | 11 (61.1) | 3 (16.7) | 1 (5.6) | |||||||||
No (n = 93) | 56 (60.2) | 15 (16.1) | 3 (3.2) | |||||||||
Carotid dissection | 1.000 | 1.000 | 1.000 | |||||||||
Yes (n = 2) | 1 (60.6) | 0 | 0 | |||||||||
No (n = 109) | 66 (50.0) | 18 (16.5) | 4 (3.7) | |||||||||
Carotid atheromatous | 0.550 | 0.708 | 0.445 | |||||||||
Yes (n = 15) | 8 (53.3) | 3 (20.0) | 1 (6.7) | |||||||||
No (n = 96) | 59 (61.5) | 15 (15.6) | 3 (3.1) | |||||||||
Symptomatic carotid | 0.326 | 1.000 | 0.512 | |||||||||
Yes (n = 18) | 9 (50.0) | 3 (16.7) | 1 (5.6) | |||||||||
No (n = 93) | 58 (62.4) | 15 (16.1) | 3 (3.2) | |||||||||
Intracranial stenosis | 0.400 | 1.000 | 1.000 | |||||||||
Yes (n = 6) | 5 (83.3) | 1 (16.7) | 0 | |||||||||
No (n = 105) | 62 (59.0) | 17 (16.2) | 4 (3.8) | |||||||||
Atrial flutter | 0.648 | 0.512 | 1.000 | |||||||||
Yes (n = 4) | 2 (50.0) | 1 (25.0) | 0 | |||||||||
No (n = 107) | 65 (60.7) | 17 (15.9) | 4 (3.7) | |||||||||
Atrial fibrillation | 0.004 | 0.012 | 1.000 | |||||||||
Yes (n = 29) | 11 (37.9) | 9 (31.0) | 1 (3.4) | |||||||||
No (n = 82) | 56 (68.3) | 9 (11.0) | 3 (3.7) | |||||||||
Aortic arch | 1.000 | 0.299 | 1.000 | |||||||||
Yes (n = 2) | 1 (50.0) | 1 (50.0) | 0 | |||||||||
No (n = 109) | 66 (60.6) | 17 (15.6) | 4 (3.7) | |||||||||
Cardiac heart failure | 0.155 | 0.299 | 1.000 | |||||||||
Yes (n = 2) | 0 | 1 (50.0) | 0 | |||||||||
No (n = 109) | 67 (61.5) | 17 (15.6) | 4 (3.7) | |||||||||
PFO | 0.155 | 1.000 | 1.000 | |||||||||
Yes (n = 2) | 0 | 0 | 0 | |||||||||
No (n = 109) | 67 (61.5) | 18 (16.5) | 4 (3.7) | |||||||||
Extracardiac shunt | 0.396 | 0.162 | 1.000 | |||||||||
Yes (n = 1) | 0 | 1 (100.0) | 0 | |||||||||
No (n = 110) | 67 (61.5) | 17 (15.5) | 4 (3.6) | |||||||||
Thrombolysis | 0.751 | 0.021 | 1.000 | |||||||||
Yes (n = 26) | 21 (70.0) | 8 (30.8) | 1 (3.8) | |||||||||
No (n = 85) | 46 (56.8) | 10 (11.8) | 3 (3.5) | |||||||||
MES | 0.547 | 16.83 (2.01–141) | ||||||||||
Number of MES | ||||||||||||
0 | 62 (60%) | 0.429 | 16 (15.5%) | 0,154 | 2 (1.9%) | 0.017 | ||||||
1 | 3 (100%) | 0 (0%) | 1 (33%) | |||||||||
3 | 1 (50%) | 0 (0%) | 1 (50%) | |||||||||
5 | 1 (33%) | 2 (66%) | 0 (0%) | |||||||||