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Table 3 Performance parameters of the different VExUS grading systems assessed at ICU admission to predict acute kidney injury in 145 patients after cardiac surgery

From: Quantifying systemic congestion with Point-Of-Care ultrasound: development of the venous excess ultrasound grading system

Grading system

Grade

Specificity (CI)

Sensitivity (CI)

+LR (CI)

− LR (CI)

VExUS A

1

41% (31–51%)

73% (59–85)

1.24 (0.98–1.57)

0.65 (0.40–1.07)

2

67% (56–76%)

55% (40–69%)

1.65 (1.13–2.42)

0.67 (0.49–0.93)

3

86% (78–92%)

39% (26–54%)

2.86 (1.54–5.30)

0.71 (0.56–0.89)

VExUS B

1

41% (31–51%)

73% (59–85%)

1.24 (0.98–1.57)

0.65 (0.40–1.07)

2

67% (56–76%)

55% (40–69%)

1.65 (1.13–2.42)

0.67 (0.49–0.93)

3

77% (67–85%)

43% (29–58%)

1.87 (1.15–3.05)

0.74 (0.58–0.95)

VExUS C

1

41% (31–51%)

73% (59–85%)

1.24 (0.98–1.57)

0.65 (0.40–1.07)

2

87% (78–92%)

39% (26–54%)

2.86 (1.55–5.30)

0.71 (0.56–0.89)

3

96% (89–99%)

27% (15–41%)

6.37 (2.19–18.5)

0.77 (0.65–0.91)

VExUS D

2

52% (42–62%)

61% (46–74%)

1.28 (0.94–1.73)

0.74 (0.51–1.08)

3

70% (59–79%)

45% (31–60%)

1.49 (0.96–2.29)

0.79 (0.61–1.03)

VExUS E

2

79% (69–87%)

41% (27–56%)

1.96 (1.17–3.28)

0.75 (0.59–0.95)

3

93% (85–97%)

29% (17–43%)

3.92 (1.69–9.07)

0.77 (0.64–0.92)

Portal Doppler only

Mild

73% (64–82%)

39% (25–52%)

1.46 (0.90–2.37)

0.83 (0.65–1.08)

Severe

91% (86–97%)

27% (14–39%)

3.12 (1.39–7.01)

0.80 (0.67–0.96)

Hepatic vein Doppler only

Mild

56% (46–66%)

51% (37–65%)

1.16 (0.81–1.66)

0.88 (0.62–1.23)

Severe

84% (76–91%)

34% (20–48%)

2.11 (1.15–3.89)

0.79 (0.63–0.98)

Renal Doppler only

Mild

80% (72–88%)

45% (31–59%)

2.27 (1.36–3.77)

0.69 (0.52–0.90)

Severe

94% (89–99%)

25% (12–37%)

3.92 (1.57–9.81)

0.81 (0.68–0.95)

CVP

≥ 8 mmHg

48% (37–59%)

77% (61–88%)

1.47 (1.13–1.90)

0.49 (0.28–0.86)

≥ 10 mmHg

66% (55–75%)

58% (42–73%)

1.71 (1.16–2.51)

0.64 (0.44–0.91)

≥ 12 mmHg

83% (73–90%)

33% (20–49%)

1.91 (1.02–3.59)

0.81 (0.66–1.01)

  1. CI confidence intervals, CVP central venous pressure, +LR positive likelihood ratio, − LR negative likelihood ratio