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Table 1 Clinical and echocardiographic characteristics of study subjects

From: Changes in speckle-tracking-derived mechanical dispersion index are associated with 30-day readmissions in acute heart failure

Parameter 30-day outcome p value Comparison EMROC cohort (n = 235)
Favorable (n = 18) Readmission (n = 13)
Age, mean in years 57.2 55.9 0.77 58.5
Gender, female n (%) 7 (38.9%) 8 (61.5%) 0.29 116 (49.4%)
African American, n (%) 18 (100%) 13 (100%) 1.0 218 (92.8%)
DM, n (%) 7 (38.9%) 4 (30.8%) 0.72 100 (42.6%)
CAD, n (%) 9 (50.0%) 10 (76.9%) 0.16  
HTN, n (%) 16 (88.9%) 11 (84.6%) 1.0 224 (95.3%)
CKD, n (%) 5 (27.8%) 2 (15.4%) 0.67 76 (32.3%)
COPD, n (%) 7 (38.9%) 5 (38.5%) 1.0 109 (46.6%)
Systolic BP at baseline, mean 165.3 mm Hg 172.9 mm Hg 0.51 160.0 mm Hg
NIPPV support 4 (22.2%) 2 (15.4%) 0.63 10 (4.3%)
NT-proBNP, median 6787 pg/mL (IQR 3353–9077) 6022 pg/mL (IQR 2179–10,434) 0.61 3345 pg/mL (IQR 1335–8413)
Any troponin in first 23 h > 99th percentile limit, n (%) 10 (55.6%) 8 (61.5%) 0.74 140 (59.6%)
Creatinine, mean 1.88 mg/dL 1.68 mg/dL 0.78 1.2 mg/dL
Vasodilator therapy, n (%) 5 (27.8%) 6 (46.2%) 0.45 77 (32.8%)
Inotropic therapy, n (%) 0 (0%) 0 (0%) 1.0 1 (0.4%)
Diuretic dosage in first 23 h, mean 63.3 mg 67.7 mg 0.75 42.6 mg
Echocardiographic data
 LVEF (%), mean (95% CI) 32 (26, 41) 33 (26, 41) 0.98 43%
 Baseline GLS (%), mean (95% CI) − 5.7 (− 7.0, − 4.3) − 7.7 (− 10.0, − 5.4) 0.09 N/A
 23-h GLS (%), mean (95% CI) − 7.1 (− 8.6, − 5.7) − 8.2 (− 10.6, − 5.7) 0.42 N/A
 Absolute change GLS (%), mean (95% CI) − 1.48 (− 2.5, − 0.43) − 0.45 (− 1.49, 0.59) 0.09 N/A
 Percentage change GLS (%), mean (95% CI) − 61.9 (− 126, 2.3) − 8.1 (− 27.3, 11.1) 0.08 N/A
 Baseline MDI (ms), mean (95% CI) 84 (67, 101) 66 (55, 76) 0.07 N/A
 23-h MDI (ms), mean (95% CI) 64 (57, 70) 70 (59, 81) 0.26 N/A
 Absolute change MDI (ms), mean (95% CI) − 20 (− 34.6, − 5.4) 4.3 (− 6.8, 15.3) 0.007 N/A
 Percentage change MDI (%), mean (95% CI) − 16.7 (− 28.8, − 4.7) 11.0 (− 6.8, 28.8) 0.008 N/A
  1. EMROC Emergency Medicine Research and Outcomes Consortium, DM diabetes mellitus, CAD coronary artery disease, HTN hypertension, CKD chronic kidney disease, COPD chronic obstructive pulmonary disease, BP blood pressure, NIPPV non-invasive positive pressure ventilation, LVEF left ventricular ejection fraction, GLS global longitudinal strain, MDI mechanical dispersion index