Table 1 Study population demographics and clinical characteristics

Demographics

 Age, years^a

 Sex-male, n (%)

Time ICU admission—CO study, days^a

Primary diagnosis, n (%)

 Septic shock

 Respiratory failure

 Surgical

 Trauma

 Other

Secondary diagnoses, n (%)

 DM

 Hepatic cirrhosis

 COPD

 Solid cancer

 CRF

Vital signs

 Heart rate, bpm^a

 MAP, mmHg^a

 BMI, kg/m^2a

Vasopressors and inotropes

 Noradrenaline, n (%)

 Noradrenaline, mcg/kg/min^a

 Dobutamine, n (%)

 Dobutamine, mcg/kg/min^a

Hemodynamics

 CVP, mmHg^a

 PAP, mmHg^a

 PCWP, mmHg^a

Ventilation

 Mechanical ventilation, n (%)

 FiO₂, %^a

 PEEP, cmH₂O^a

 Tidal volume, mL^a

 PaO₂, mmHg^a

 PaO₂/FiO ^a₂

Severity of illness

 SOFA^a

 APACHE II^a

 Mortality, n (%)