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Table 1 Clinical and biochemical variables of failed and successful extubation groups

From: The impact of heart, lung and diaphragmatic ultrasound on prediction of failed extubation from mechanical ventilation in critically ill patients: a prospective observational pilot study

  Failed extubation (n = 11) Successful extubation (n = 42) Unadjusted OR (95% CI) p value
Characteristics
 Male n (%) 10 (90.9) 24 (57.1) 0.13 (0.01–1.14) 0.06
 Age, years median (IQR) 77.0 (65.0–81.0) 63.5 (45.7–73.3.0) 1.05 (0.99–1.11) 0.06
 Ideal body weight (kg) median (IQR) 61.0 (54.7–63.9) 62.3 (54.6–66.2) 0.96 (0.87–1.06) 0.44
 BMI kg/m2 median (IQR) 27.0 (23.3–35.1) 27.0 (24.1–31.0) 1.0 (0.9–1.11) 0.95
 Ischaemic heart disease n (%) 7 (63.6) 9 (21.4) 6.41 (1.53–26.88) 0.01
 Heart failure n (%) 3 (27.3) 5 (11.9) 2.77 (0.54–14.05) 0.21
 Diabetes mellitus n (%) 6 (54.5) 9 (21.4) 4.40 (1.08–17.79) 0.03
 COPD n (%) 3 (27.3) 6 (14.3) 2.25 (0.46–10.96) 0.31
ICU severity score
 APACHE II median (IQR) 20.0 (17–23) 20.0 (15.0–23.3) 1.06 (0.94–1.20 0.31
 APACHE III median (IQR) 82.0 (61.0–97.0) 74.5 (60.5–89.5) 1.02 (0.99–1.04) 0.21
 SAPS II median (IQR) 42.0 (33.0–46.0) 46.0 (36.0–57.3) 0.99 (0.94–1.04) 0.72
Weaning trial
 Respiratory rate (breath/min) median (IQR) 24 (18–30) 18 (15–23) 1.14 (1.01–1.27) 0.02
 Tidal volume (l) median (IQR) 0.48 (0.39–0.58) 0.51 (0.41–0.75) 0.11 (0.00–5.76) 0.27
 Pressure support (cmH2O) median (IQR) 0.0 (0.0–10.0) 0.0 (0.0–7.2) 1.04 (0.89–1.22) 0.58
ICU outcomes
 Extubation failure n (%)
  ICU LOS (day) median (IQR) 10.5 (9.7–17.5) 7.9 (5.5–13.0) 1.14 (0.99–1.25) 0.06
  Time from extubation to ICU discharge (days) median (IQR) 4.1 (3.1–7.1) 1.9 (1.0–5.1) 1.13 (0.95–1.34) 0.14
  Hospital LOS (day) median (IQR) 19.2 (16.1–33.1) 16.4 (11.2–24.1) 1.00 (0.96–1.04) 0.71
  In-hospital mortality n (%) 2 (18.2) 3 (7.1) 0.34 (0.05–2.38) 0.28
  Duration of MV (h) median (IQR) 175.0 (99.1–238.5) 130.6 (93.7–180.5) 1.00 (0.99–1.01) 0.11
  1. APACHE acute physiology age and chronic health evaluation, BMI body mass index, BNP B-type natriuretic peptide, COAD chronic obstructive airway disease, H LOS hospital length of stay, ICU LOS intensive care unit length of stay, SAPS simplified acute physiology score, IQR interquartile range