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Table 1 Characteristics of patients included in the study

From: Lung and diaphragm ultrasound as predictors of success in weaning from mechanical ventilation

Variables

All patients (69)

SW (44)

FW (25)

P value

Sex (men)a

43 (62.3)

26 (63.4)

15 (62.5)

0.8

Age (years)b

66 (53, 78)

65 (53, 78)

69 (64, 78)

0.37

Time on MV (days)b

4 (3, 7)

4 (2, 6)

5 (3, 9)

0.04

Time SBT-extubation (minutes)b

120 (30, 120)

120 (30, 120)

60 (30, 120)

0.15

Mode of STB

 T−T

29 (42%)

17 (38.6%)

12 (48%)

0.14

 PS 8 and PEEP 5

34 (49%)

21 (47.7%)

13 (52%)

 

 T−T + PS 8 PEEP 5

6(9%)

6 (13.6%)

0

 

Comorbiditya

 Chronic heart disease

18 (26)

14 (31.8)

4 (16)

0.25

 Neurological disease

18 (26)

12 (27.3)

6 (24)

0.99

 COPD

13 (18.8)

5 (11.4)

8 (32)

0.05

 Diabetes mellitus

19 (27.5)

12 (27.3)

7 (28)

0.99

 Cancer

8 (11.6)

4 (9.1)

4 (16)

0.45

 Chronic kidney failure

12 (17.4)

6 (13.6)

6 (24)

0.33

 Liver disease

8 (11.6)

3 (6.8)

5 (20)

0.36

Pathology at ICU admissiona

 Neurological disease

29 (42)

18 (41)

11 (44)

 

 Respiratory disease

24 (34, 8)

16 (36.4)

8 (32)

 

 Cardiovascular disease

10 (14.5)

8 (18.2)

2 (8)

0.7

 Sepsis

7 (10.1)

5 (11.4)

2 (8)

 

 Digestive pathology

4 (5.8)

1 (2.3)

3 (12)

 

 Polytrauma

1 (1.4)

1 (2.3)

0

0.7

LUSmb

6 (4, 8)

5 (3, 7)

8 (7, 11)

0.0001

TI (%)b

36 (27, 41)

38 (31, 45)

27 (20, 40)

0.003

APACHE II on SBT dayb

4 (2, 6)

4 (2, 6)

5 (3, 9)

0.07

VE (L/min)b

8.6 (7.5, 10)

8.25 (7.3, 9.8)

9 (8.1, 11.6)

0.13

Compliance (mL/cm H2O)b

56 (41, 67)

55.5 (43, 69)

59 (40.5, 67)

0.86

PIMax (cm H2O)b

− 25 (− 23, − 25)

− 25 (− 25, − 18)

− 25 (− 26, − 24)

0.28

P0.1 (cm H2O)b

1 (1, 3)

1 (1, 3)

1.5 (1, 2.5)

0.47

RSBI (breaths/min/L)b

35 (20, 50)

31 (20, 43)

37 (30, 54)

0.16

RR (breaths/min)b

17 (15, 20)

17 (14, 19)

19 (16, 22)

0.09

Tidal volume (ml)b

400 (450, 585)

508 (452, 572)

500 (440, 600)

0.71

FiO2 (%)b

30 (28, 35)

30 (28, 35)

30 (28, 35)

0.83

SpO2 (%)b

98 (97, 100)

99 (97, 100)

97 (96, 99)

0.027

PaCO2 (mm Hg)b

40 (36, 46)

41 (36, 45.6)

39.6 (37, 45)

0.63

PaO2, (mm Hg)b

93 (79, 115)

96.5 (83, 117)

92 (74, 115)

0.61

pHb

7.42 (7.32, 7.47)

7.4 (7.3, 7.5)

7.4 (7.4, 7.4)

0.93

Lactate (mmol/L)b

1.2 (1, 1.7)

1.2 (1, 1.5)

1.3 (1.1, 2)

0.2

ICU mortalitya

7 (14)

1 (2.3)

6 (24)

0.005

Hospital mortalitya

11 (16)

3 (6.8)

8 (32)

0.003

ICU stay (days)b

11 (7, 19)

8 (6, 15)

18 (11, 21)

0.002

Hospital stay (days)b

19 (14, 30)

17 (13.5, 31)

23 (17, 30)

0.08

  1. SW, successful weaning; FW, failed weaning; MV, mechanical ventilation; T−T, disconnection with T-tube with oxygen; PS 8 and PEEP, 5 disconnection with pressure support and 5 cm H2O positive end-expiratory pressure; ICU, intensive care unit; LUSm, modified lung ultrasound score; TI, diaphragm thickness index; APACHE II, acute physiology and chronic health evaluation II; SBT, spontaneous breathing trial; VE, minute ventilation; PIMax, maximal inspiratory pressure; P0.1, airway occlusion pressure; RR, respiratory rate; RSBI, rapid shallow breathing index; FiO2, fraction of inspired oxygen; SpO2, oxygen saturation; PaCO2, partial pressure of carbon dioxide; PaO2, partial pressure of oxygen; ICU, intensive care unit
  2. an (%), bMedian (IQR)