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Table 1 Characteristics of patients included in the study

From: Lung and diaphragm ultrasound as predictors of success in weaning from mechanical ventilation

Variables All patients (69) SW (44) FW (25) P value
Sex (men)a 43 (62.3) 26 (63.4) 15 (62.5) 0.8
Age (years)b 66 (53, 78) 65 (53, 78) 69 (64, 78) 0.37
Time on MV (days)b 4 (3, 7) 4 (2, 6) 5 (3, 9) 0.04
Time SBT-extubation (minutes)b 120 (30, 120) 120 (30, 120) 60 (30, 120) 0.15
Mode of STB
 T−T 29 (42%) 17 (38.6%) 12 (48%) 0.14
 PS 8 and PEEP 5 34 (49%) 21 (47.7%) 13 (52%)  
 T−T + PS 8 PEEP 5 6(9%) 6 (13.6%) 0  
Comorbiditya
 Chronic heart disease 18 (26) 14 (31.8) 4 (16) 0.25
 Neurological disease 18 (26) 12 (27.3) 6 (24) 0.99
 COPD 13 (18.8) 5 (11.4) 8 (32) 0.05
 Diabetes mellitus 19 (27.5) 12 (27.3) 7 (28) 0.99
 Cancer 8 (11.6) 4 (9.1) 4 (16) 0.45
 Chronic kidney failure 12 (17.4) 6 (13.6) 6 (24) 0.33
 Liver disease 8 (11.6) 3 (6.8) 5 (20) 0.36
Pathology at ICU admissiona
 Neurological disease 29 (42) 18 (41) 11 (44)  
 Respiratory disease 24 (34, 8) 16 (36.4) 8 (32)  
 Cardiovascular disease 10 (14.5) 8 (18.2) 2 (8) 0.7
 Sepsis 7 (10.1) 5 (11.4) 2 (8)  
 Digestive pathology 4 (5.8) 1 (2.3) 3 (12)  
 Polytrauma 1 (1.4) 1 (2.3) 0 0.7
LUSmb 6 (4, 8) 5 (3, 7) 8 (7, 11) 0.0001
TI (%)b 36 (27, 41) 38 (31, 45) 27 (20, 40) 0.003
APACHE II on SBT dayb 4 (2, 6) 4 (2, 6) 5 (3, 9) 0.07
VE (L/min)b 8.6 (7.5, 10) 8.25 (7.3, 9.8) 9 (8.1, 11.6) 0.13
Compliance (mL/cm H2O)b 56 (41, 67) 55.5 (43, 69) 59 (40.5, 67) 0.86
PIMax (cm H2O)b − 25 (− 23, − 25) − 25 (− 25, − 18) − 25 (− 26, − 24) 0.28
P0.1 (cm H2O)b 1 (1, 3) 1 (1, 3) 1.5 (1, 2.5) 0.47
RSBI (breaths/min/L)b 35 (20, 50) 31 (20, 43) 37 (30, 54) 0.16
RR (breaths/min)b 17 (15, 20) 17 (14, 19) 19 (16, 22) 0.09
Tidal volume (ml)b 400 (450, 585) 508 (452, 572) 500 (440, 600) 0.71
FiO2 (%)b 30 (28, 35) 30 (28, 35) 30 (28, 35) 0.83
SpO2 (%)b 98 (97, 100) 99 (97, 100) 97 (96, 99) 0.027
PaCO2 (mm Hg)b 40 (36, 46) 41 (36, 45.6) 39.6 (37, 45) 0.63
PaO2, (mm Hg)b 93 (79, 115) 96.5 (83, 117) 92 (74, 115) 0.61
pHb 7.42 (7.32, 7.47) 7.4 (7.3, 7.5) 7.4 (7.4, 7.4) 0.93
Lactate (mmol/L)b 1.2 (1, 1.7) 1.2 (1, 1.5) 1.3 (1.1, 2) 0.2
ICU mortalitya 7 (14) 1 (2.3) 6 (24) 0.005
Hospital mortalitya 11 (16) 3 (6.8) 8 (32) 0.003
ICU stay (days)b 11 (7, 19) 8 (6, 15) 18 (11, 21) 0.002
Hospital stay (days)b 19 (14, 30) 17 (13.5, 31) 23 (17, 30) 0.08
  1. SW, successful weaning; FW, failed weaning; MV, mechanical ventilation; T−T, disconnection with T-tube with oxygen; PS 8 and PEEP, 5 disconnection with pressure support and 5 cm H2O positive end-expiratory pressure; ICU, intensive care unit; LUSm, modified lung ultrasound score; TI, diaphragm thickness index; APACHE II, acute physiology and chronic health evaluation II; SBT, spontaneous breathing trial; VE, minute ventilation; PIMax, maximal inspiratory pressure; P0.1, airway occlusion pressure; RR, respiratory rate; RSBI, rapid shallow breathing index; FiO2, fraction of inspired oxygen; SpO2, oxygen saturation; PaCO2, partial pressure of carbon dioxide; PaO2, partial pressure of oxygen; ICU, intensive care unit
  2. an (%), bMedian (IQR)