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The Ultrasound Journal

Table 1 Traditional physical examination and ultrasound-assisted physical examination findings for splenomegaly

From: Point-of-care ultrasonography improves the diagnosis of splenomegaly in hospitalized patients

Condition

Reference standard

Test

n (patients)

Sensitivity (95 % CI) [TP/FN + TP]

Specificity (95 % CI) [TN/TN + FP]

p value*

LR+ (95 % CI)

LR− (95 % CI)

Splenomegaly

CT or US

Physical examination alone

39

0.40 (0.12–.77) [2/5]

0.88 (0.73–0.95) [30/34]

0.161

3.40 (0.827–13.98)

0.68 (0.33–1.41)

Physical exam + POCUS

1 (0.57–1) [5/5]

0.74 (0.57–0.85) [25/34]

0.003

3.78 (2.16–6.61)

0

  1. TP true positive, FP false positive, FN false negative, TN true negative, LR+ positive likelihood ratio, LR− negative likelihood ratio, CT computed tomography, US ultrasound
  2. * p value for Fisher’s exact test
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