Table 1 Characteristics and baseline parameters before all fluid challenges, between responders and non-responders

Age (years)

51 (38–58)

53 (38–57)

0.65

Gender (male, %)

20 (67)

17 (59)

0.71

BSA (m²)

1.65 (1.50–1.80)

1.60 (1.57–1.80)

0.72

ARDS (%)

22 (73)

21 (72)

0.83

AKI (%)

15 (50)

14 (48)

0.88

Shock diagnosis (hours)

17.5 (13–23)

27 (21.7–35)

0.0001

MAP (mmHg)

61 (60–62.8)

63 (61–64.2)

0.053

HR (beats/min)

119 (117–123)

121 (115–124)

0.63

UO (ml/kg/h)

0.4 (0.2–0.6)

0.4 (0.2 – 0.8)

0.34

Arterial Lactate (mmol/L)^a

5.3 ± 1.6

4.7 ± 1.7

0.20

ScvO2 (%)

64 ± 10.7

67 ± 10.2

0.26

SVI (ml/m²)

16 (14–18)

17 (15–19)

0.09

NE dose (mcg/kg/min)

0.33 (0.21–0.57)

0.40 (0.33–0.54)

0.36

Fluid balance (L)^a

2.12 ± 0.70

2.62 ± 0.75

0.01

Fluid loads (n)

2 (2–3)

2 (2–3)

0.19

SOFA (score)

10 (8–13)

15 (13–18)

<0.0001

PEEP (cm/H₂O)

6 (5–7)

6 (5–7)

0.71

Plateau pressure (cm/H₂O)^a

24 ± 3

24 ± 3

0.98

Tidal volume (ml/kg)

6 (6.0–6.3)

6 (6.0–6.3)

0.96