Table 2 Incidence and clinical characteristics of diastolic dysfunction by ASE guidelines on initial echocardiogram
Characteristic | Grade 0 (normal) | Grade I (impaired relaxation) | Grade II (pseudonormal) | Grade III (restrictive) | p value (any difference among groups) | p value (grade I vs grades II and III) |
|---|---|---|---|---|---|---|
Patients (N, %) | 47 (64%) | 8 (11%) | 17 (23%) | 2 (3%) | Â | Â |
Median age (years) | 53 | 64 | 54 | 47 | 0.03 | 0.01 |
Female (%) | 44.7% | 62.5% | 58.8% | 50.0% | 0.72 | 1.0 |
APACHE II | 21.0 | 25.0 | 25.0 | 23.5 | 0.16 | 0.79 |
Percent on vasopressors | 40.1% | 25.0% | 35.3% | 50.0% | 0.89 | 0.68 |
BMI (kg/m2) | 28.3 | 26.4 | 33.8 | 32.9 | 0.31 | 0.07 |
e’ (cm/s) | 9.97 | 5.82 | 7.16 | 3.99 | <0.01 | 0.04 |
E/e’ | 9.1 | 12.0 | 12.5 | 26.7 | 0.01 | 0.67 |
DT (ms) | 151 | 169 | 187 | 123 | 0.28 | 0.67 |
E/A | 1.16 | 0.72 | 0.93 | 3.30 | <0.01 | <0.01 |
IVC diameter (cm) | 1.90 | 1.91 | 1.94 | 2.18 | 0.85 | 0.89 |
IVC collapsibility (%) | 32.7% | 27.0% | 23.6% | 11.1% | 0.18 | 0.55 |
Cardiac output (L/min) | 6.4 | 4.0 | 6.5 | 4.2 | 0.10 | 0.45 |
VFD (days) | 20.5 | 17.2 | 23.6 | 26.5 | 0.76 | 0.34 |
ICU-free days | 17.9 | 15.8 | 18.9 | 25.5 | 0.98 | 0.96 |
Mortality (%) | 12.8% | 37.5% | 5.9% | 0% | 0.19 | 0.06 |
IVF administered prior to TTE #1 (L) | 3.5 | 2.6 | 5.5 | 5.4 | 0.07 | 0.05 |
IVF administered in 24 h after TTE #1 (L) | 4.0 | 2.7 | 3.2 | 5.5 | 0.3 | 0.6 |
CVP (mm Hg) | 11 | 11 | 12 | 11 | 0.89 | 0.84 |